Methods for the accumulation and retention of immune-enhancing, bacterial-derived ribonucleotides (ORN) in bacteria
US7678557B2 · kind B2 · utility
Inventor
Key dates
| Filing date | Nov 22, 2005 |
| Grant date | Mar 16, 2010 |
| Priority date | — |
| Expiry date | Feb 9, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/55561
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to methods for the accumulation and retention of immune-enhancing, bacterial-derived ribonucleotides smaller than 10,000 Daltons (ORN<10 kDa) in bacteria that are produced when bacteria are grown naturally, allowing the pH of the growth medium to become acidic. The immune-enhancing, bacterial-derived ribonucleotides (ORN) and bacteria comprising ORN are useful in the preparation of animal feed or animal drinking water as well as for use in enhancing the immune system of an animal and/or its resistance to infection. The invention also discloses methods of preventing the loss of ORN during bacterial production and storage as well as methods to aid in the release of ORN when consumed by an animal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.