Flow cell array and the utilization thereof for multianalyte determination

US7678565B2 · kind B2 · utility

Assignee

• BAYER TECHNOLOGY SERVICES GMBH · DE

Inventors

• Eveline Schürmann-Mader · Zeihen, CH
• Andreas Peter Abel · Basel, CH
• Martin Andreas Bopp · Basel, CH
• Gert Ludwig Duveneck · Bad Krozingen, DE
• Markus Ehrat · Magden, CH
• Gerhard Matthias Kresbach · Staufen, DE
• Michael Pawlak · Laufenbürg, DE
• Nania Graciela Schärer-Hernández · Gelterkinden, CH
• Eginhard Schick · Rheinfelden (Baden), DE

Key dates

• Filing date: Feb 21, 2008
• Grant date: Mar 16, 2010
• Expiry date: Jul 15, 2028

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2021/0346
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents. An arrangement of one or more sample compartments includes a base plate and a body combined with the base plate in such a way that one or more recesses for generation of one or more flow cells fluidically sealed against one another, each with at least one inlet and one outlet, are formed between the base plate and the body, wherein at least one outlet of each flow cell is joined with a reservoir fluidically connected with the flow cell, the reservoir being operable to receive liquid exiting the flow cell, besides methods for its manufacturing and their use.