Method for enhancing T cell reactivity toward tumour antigens
US7678758B2 · kind B2 · utility
0Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 16, 2002 |
| Grant date | Mar 16, 2010 |
| Priority date | — |
| Expiry date | Jun 28, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/5152
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a method of vaccinating a patient against a tumor by administering an agent to reduce or prevent interaction between Notch and a Notch ligand, or expression or processing of Notch or a Notch ligand. In one embodiment, this is accomplished by administering to the patient a tumor antigen expressed by the tumor and exposing an antigen presenting cell in the patient to an agent that reduces or prevents interaction, expression or processing of Notch or a Notch ligand in a T cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.