Nitroheteroaryl-containing rifamycin derivatives
US7678791B2 · kind B2 · utility
2Cited by
8References
7Claims
0Family size
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Key dates
| Filing date | Jul 12, 2007 |
| Grant date | Mar 16, 2010 |
| Priority date | — |
| Expiry date | Jan 21, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Substituted rifamycin derivatives in which a nitroimidazole, nitrothiazole or nitrofuran pharmacophore is covalently bonded to a rifamycin, methods of using the rifamycin derivatives, and pharmaceutical compositions containing the rifamycin derivatives are disclosed. Methods of synthesizing these substituted rifamycin derivatives are also disclosed. The rifamycin derivatives possess antibacterial activity, and are effective against a number of human and veterinary pathogens in the treatment of bacterial diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.