Alzheimer's disease diagnosis based on mitogen-activated protein kinase phosphorylation
US7682807B2 · kind B2 · utility
3Cited by
4References
62Claims
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Key dates
| Filing date | Feb 27, 2002 |
| Grant date | Mar 23, 2010 |
| Priority date | — |
| Expiry date | Apr 29, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2821
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of diagnosing Alzheimer's disease in a patient comprises determining whether the phosphorylation level of an indicator protein in cells of the patient after stimulus with an activator compound is abnormally elevated as compared to a basal phosphorylation level, the indicator protein being e.g. Erk1/2 and the activator compound being e.g. bradykinin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.