7-azaindoles, their use as inhibitors of phosphodiesterase 4, and a method for synthesizing them

US7683074B2 · kind B2 · utility

Assignee

• Biotie Therapies, Inc. · US

Inventors

• Norbert Höfgen · Radeberg, DE
• Ute Egerland · Radebeul, DE
• Thomas Kronbach · Radebeul, DE
• Degenhard Marx · Radebeul, DE
• Stefan Szelenyi · Arnstorf, DE
• Hildegard Kuss · Dresden, DE
• Emmanuel Polymeropoulos · Frankfurt, DE

Key dates

• Filing date: Mar 10, 2008
• Grant date: Mar 23, 2010
• Expiry date: Sep 3, 2028

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

7-azaindoles inhibit phosphodiesterase 4 (PDE4). Methods for preparing these compounds and methods of treating arthritis and other conditions with the compounds are also provided.