Patent · US Expired

Process for the preparation of optically-active compounds

US7683190B2 · kind B2 · utility

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1References

1Claims

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Assignee

Givaudan SA · CH

Inventors

Georg Frater · Winterthur, CH
Urs Mueller · Stintenberger Straße, CH

Key dates

Filing date	Jul 26, 2005
Grant date	Mar 23, 2010
Priority date	—
Expiry date	May 26, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D307/92
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A method of preparing enatiomerically enriched 3a,6,6,9a-tetramethyl-dodecahydro-naphtho[2,1-b]furan, formula (I), from (E,E)-homofarnesic acid or (E)-monocyclohomofarnesic acid by (a) reacting firstly with a chiral alcohol, (b) reacting the product of (a) with an acid to cause a first cyclization, (c) producing an alcohol by reacting the product of (b) with a reducing agent and (d) causing a second cyclization by reacting the product of (c) with an acid. The product of this process gives a mixture of both enantiomers with one in excess.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.