Methods and compositions for the correlation of single nucleotide polymorphisms in the vitamin K epoxide reductase gene and warfarin dosage
US7687233B2 · kind B2 · utility
8Cited by
13References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 23, 2004 |
| Grant date | Mar 30, 2010 |
| Priority date | — |
| Expiry date | Sep 23, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/172
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a method of identifying a human subject having increased or decreased sensitivity to warfarin, comprising detecting in the subject the presence of a single nucleotide polymorphism in the VKOR gene, wherein the single nucleotide polymorphism is correlated with increased or decreased sensitivity to warfarin, thereby identifying the subject having increased or decreased sensitivity to warfarin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.