Compositions and methods for diagnosing and treating neuropsychiatric disorders

US7687235B2 · kind B2 · utility

Assignee

• Board of Trustees of the Leland Stanford Junior University · US

Inventors

• Huda Akil · Ann Arbor, US
• Mary Atz · Tustin, US
• William Bunney · Laguna Beach, US
• William Byerley · San Francisco, US
• Kathleen Casey · Santa Ana, US
• Prabhakara V. Choudary · Davis, US
• Simon J. Evans · Milan, US
• Edward G. Jones · Winters, US
• Jun Li · Palo Alto, US
• Juan F. Lopez · Ann Arbor, US
• Richard M. Myers · Huntsville, US
• Brandi Rollins · Laguna Hills, US
• Robert C. Thompson · Boulder, US
• Hiroaki Tomita · Kyoto, JP
• Marquis Vawter · Watsonville, US
• Stanley Watson · Ann Arbor, US

Key dates

• Filing date: Mar 31, 2006
• Grant date: Mar 30, 2010
• Expiry date: May 16, 2027

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/304
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention provides methods for diagnosing mental disorders (e.g., psychotic disorders such as schizophrenia and mood disorders such as major depression disorder and bipolar disorder). The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.