Method for determining specific groups constituting heparins or low molecular weight heparins
US7687274B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 14, 2008 |
| Grant date | Mar 30, 2010 |
| Priority date | — |
| Expiry date | Jan 14, 2028 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The invention provides methods for analyzing heparins, low-molecular-weight heparins, ultralow-molecular-weight heparins, and oligosaccharides by high performance liquid chromatography a stationary phase dynamically coated with a quaternary ammonium salt. The methods of the invention may be used to analyze samples without pre-treatment or to analyze samples that have been partially or exhaustively depolymerised and, optionally, reduced. Specific saccharides can be detected.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.