Substituted piperidines

US7687495B2 · kind B2 · utility

Assignee

• Speedel Experimenta AG · CH

Inventors

• Peter Herold · Allschwil, CH
• Robert Mah · Muttenz, CH
• Vincenzo Tschinke · Allschwil, CH
• Christiane Marti · Allschwil, CH
• Stefan Stutz · Basel, CH
• Stjepan Jelakovic · Allschwil, CH
• Zenon D. Konteatis · Floral Hill, US
• Jennifer L. Ludington · Lansdale, US
• Michael Quirmbach · Basel, CH
• Aleksandar Stojanovic · Allschwil, CH
• Dirk Behnke · Weil am Rhein, DE
• Frank Hollinger · Barwala, IN

Key dates

• Filing date: Mar 14, 2008
• Grant date: Mar 30, 2010
• Expiry date: Mar 14, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Substituted piperidines of formulae (I) and (II) with the substituent definitions as explained in the specification. The compounds are suitable in particular as renin inhibitors and are highly potent.