Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes

US7687510B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Heike Gielen-Haertwig · Monheim, DE
• Volkhart Min-Jian Li · Velbert, DE
• Ulrich Rosentreter · Binnen, DE
• Karl-Heinz Schlemmer · Wuppertal, DE
• Swen Allerheiligen · Wuppertal, DE
• Leila Telan · Wuppertal, DE
• Lars Bärfacker · Oberhausen, DE
• Jörg Keldenich · Wuppertal, DE
• Mary F. Fitzgerald · Yarnton, GB
• Kevin Nash · Seffner, US
• Barbara Albrecht · Wuppertal, DE
• Dirk Meurer · Wunstorf, DE

Key dates

• Filing date: Aug 28, 2003
• Grant date: Mar 30, 2010
• Expiry date: Jun 4, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to novel heterocyclic derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases.