Patent · US Active

System for controlling flow into chromatographic column using transfer line impedance

US7691181B2 · kind B2 · utility

10Cited by
16References
29Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 11, 2008
Grant dateApr 6, 2010
Priority date—
Expiry dateDec 22, 2028

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2030/324
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A system for controlling the flow rate into a chromatographic column is disclosed generally comprising communicating a fluid to the column through a transfer line, measuring the inlet pressure, determining the outlet pressure, and adjusting the applied pressure until the inlet and outlet pressures produce a desired flow rate for the transfer line outlet. In certain embodiments, the applied pressure is adjusted by controlling a proportional valve. In some embodiments, the outlet pressure is determined by measuring the pressure drop across the transfer line and calculating the outlet pressure from the measured inlet pressure and the pressure drop.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.