Ovarian cancer cell and myeloma cell surface glycoproteins, antibodies thereto, and uses thereof
US7691376B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | May 24, 2007 |
| Grant date | Apr 6, 2010 |
| Priority date | — |
| Expiry date | Jun 15, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to cell surface antigens found on myeloma cells and on ovarian cancer cells that are recognized by monoclonal antibodies, and antibody binding fragments thereof, as described. The monoclonal antibodies of the invention are capable of being used for therapeutic, screening, diagnostic and cell purification purposes. A representative and exemplified monoclonal antibody of the present invention recognizes and binds to an epitope common to a surface antigen that is expressed on multiple myeloma cells and to a surface antigen that is expressed on ovarian cancer cells. The function of this monoclonal antibody both in vivo and in vitro is demonstrated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.