Methods of secretory vimentin detection and modulation
US7691582B2 · kind B2 · utility
2Cited by
0References
9Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 24, 2003 |
| Grant date | Apr 6, 2010 |
| Priority date | — |
| Expiry date | Jan 27, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods for screening and modulating the bioavailability of extracellular secretory vimentin. In particular, the present invention provides inhibitors and activators of secretory vimentin including antibodies, small interfering RNAs, and antisense oligonucleotides. The present invention thus provides novel drug targets for enhanced anti-microbial response, and methods of using such modulators to beneficially alter the pathophysiologic effects of secretory vimentin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.