Benzimidazole carboxamides as raf kinase inhibitors

US7691870B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Hans-Peter Buchstaller · Griesheim, DE
• Matthias Wiesner · Seeheim-Jugenheim, DE
• Frank Zenke · Darmstadt, DE
• Christiane Amendt · Mühltal, DE
• Matthias Grell · Darmstadt, DE
• Christian Sirrenberg · Darmstadt, DE

Key dates

• Filing date: Jun 11, 2004
• Grant date: Apr 6, 2010
• Expiry date: Jun 11, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D403/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to benzimidazole carboxamides of formula I, the use of the compounds of formula I of as inhibitors of one or more kinases, the use of the compounds of formula I for the manufacture of pharmaceutical compositions and methods of treatment, comprising administering said pharmaceutical compositions to a patients.