Exendins and exendin agonists modified with polyamino acids
US7691963B2 · kind B2 · utility
42Cited by
31References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 11, 2008 |
| Grant date | Apr 6, 2010 |
| Priority date | — |
| Expiry date | May 19, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Modified exendins and exendin agonists having an exendin or exendin agonist linked to one or more molecular weight increasing compounds, for example, polyamino acids, polyethylene glycol polymers, and related formulations and dosages and methods of administration thereof are provided. These modified exendins and exendin agonists, compositions comprising the modified exendin or the agonist thereof are useful in treating diabetes and conditions that would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying or inhibiting food intake.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.