Process for the synthesis of peptides amides by side-chain attachment to a solid phase
US7691968B2 · kind B2 · utility
5Cited by
6References
7Claims
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Key dates
| Filing date | May 2, 2003 |
| Grant date | Apr 6, 2010 |
| Priority date | — |
| Expiry date | Oct 10, 2026 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is provided for the solid-phase synthesis of a peptide amide which comprises attaching an α-nitrogen protected Cα-carboxamide amino acid to a solid support by its side chain, removing the α-nitrogen protecting group, assembling a peptide chain on said α-nitrogen and then cleaving the assembled peptide amide from the solid support. Novel amino acid analogues, peptide amides and solid-phase supports are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.