Patent · US Expired

Multi-sided immersion formation of composite structures and method

US7695686B2 · kind B2 · utility

0Cited by
18References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 9, 2004
Grant dateApr 13, 2010
Priority date
Expiry dateFeb 21, 2026

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/255
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

Sample preparation device and method for desalting and concentrating samples prior to further analysis such as by MALDI TOF and/or electro-spray ionization (ESI) mass spectrometry. The device in accordance with an embodiment of the present invention contains a three dimensional structure preferably comprising a plurality of sorptive particles entrapped in a porous polymer matrix so as to form a device capable of carrying out solid phase extraction. The device is manufactured by introducing casting solution containing polymer and optionally particles into a housing, and subsequently exposing the device to a quench bath for a time sufficient to allow for solvent exchange and precipitation to form the composite structure in the housing. The present invention is also directed towards a method of sample preparation using the device of the present invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.