Disposable sample processing module for detecting nucleic acids
US7695952B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 5, 2004 |
| Grant date | Apr 13, 2010 |
| Priority date | — |
| Expiry date | Apr 20, 2028 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/065
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A disposable sample processing module is provided for processing DNA or RNA samples. The module includes a hybridization chamber adapted to receive an oligonucleotide covalently bonded to an internal surface of the hybridization chamber. The module also include a sample well adapted to hold a DNA or RNA sample, said sample well being coupled to the hybridization chamber, a moveable valve plate disposed between the sample well and hybridization chamber, said moveable valve plate having a first position that allows transfer of the DNA or RNA sample from the sample well to the hybridization chamber and a second position that blocks transfer to the hybridization chamber and a manifold adapted to exchange fluids with the hybridization chamber to hybridize the DNA or RNA sample with the oligonucleotide, to wash the hybridized sample and to amplify the hybridized sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.