Methods and compositions using stearoyl-CoA desaturase to identify triglyceride reducing therapeutic agents
US7696151B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Jul 11, 2005 |
| Grant date | Apr 13, 2010 |
| Priority date | — |
| Expiry date | Jun 3, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/90245
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The use of screening assays based on the role of human stearoyl-CoA desaturase-1 (“hSCD1”) in human diseases, disorders or conditions relating to serum levels of triglyceride, VLDL, HDL, LDL, total cholesterol, or production of secretions from mucous membranes, monounsaturated fatty acids, wax esters, and the like, is disclosed. Also disclosed are conventions useful in the prevention and/or treatment of such diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.