Methods for treating interleukin-18 mediated disorders with interleukin-18 binding proteins
US7696154B2 · kind B2 · utility
2Cited by
4References
15Claims
0Family size
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Key dates
| Filing date | Mar 15, 2007 |
| Grant date | Apr 13, 2010 |
| Priority date | — |
| Expiry date | Jun 28, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Interleukin-18 binding proteins which are capable of binding IL-18 and of modulating and/or blocking IL-18 activity are provided. Methods for the isolation and recombinant production, DNAs encoding them. DNA vectors expressing them, vectors useful for their expression in humans and other mammals, antibodies against them are also provided. Therapeutic uses of IL-18 binding proteins and further inhibitors of IL-18 are also provided according to the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.