Substituted benzo[d]isoxazol-3-yl amine compounds as analgesics

US7696238B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Beatrix Merla · Aachen, DE
• Robert Frank · Aachen, DE
• Gregor Bahrenberg · Monschau, DE
• Wolfgang Schroeder · Aachen, DE
• Saskia Zemolka · Aachen, DE

Key dates

• Filing date: Nov 16, 2007
• Grant date: Apr 13, 2010
• Expiry date: Nov 16, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D261/20
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Substituted benzo[d]isoxazol-3-yl amine compounds corresponding to formula Iwhich exhibit an strong affinity to the KCNQ2/3 K+ channel, and which are suitable for treating or inhibiting pain and/or disorders or disease states that are at least partly mediated by the KCNQ2/3 K+ channel.