Fluorescent probe for zinc
US7696245B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jan 30, 2004 |
| Grant date | Apr 13, 2010 |
| Priority date | — |
| Expiry date | Feb 18, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/84
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A compound represented by the following general formula (IA) or (IB) or a salt thereof which specifically traps a zinc ion and emits fluorescence, and is useful as a fluorescent probe for zinc:wherein R1 and R2 represent a hydrogen atom or a group represented by the following formula (A):wherein X1 to X4 represent a hydrogen atom, a 2-pyridylmethyl group, a 2-pyridylethyl group, a 2-methyl-6-pyridylmethyl group, or a 2-methyl-6-pyridylethyl group, provided that at least one is the group except a 2-pyridylmethyl group, and m and n represent 0 or 1, provided that they are not simultaneously 0; provided that R1 and R2 are not simultaneously hydrogen atoms; R3 and R4 represent a hydrogen atom or a halogen atom; R5 and R6 represent a hydrogen atom, an alkylcarbonyl group, or an alkylcarbonyloxymethyl group; and R7 represents a hydrogen atom or an alkyl group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.