N-carbobenzyloxy (N-CBZ)-deprotecting enzyme and uses therefor
US7696328B2 · kind B2 · utility
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2References
3Claims
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Key dates
| Filing date | Apr 28, 2008 |
| Grant date | Apr 13, 2010 |
| Priority date | — |
| Expiry date | May 27, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/78
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates to isolated or recombinant N-carbobenzyloxy-deprotecting enzyme polypeptides that catalyze the removal of carbobenzyloxy from carbobenzyloxy-protected amino acids and alcohols. Also related are isolated nucleic acids encoding N-carbobenzyloxy-deprotecting enzyme polypeptides thereof, as well as vectors and host cells comprising these nucleic acids. The invention also relates to methods of obtaining isolated nucleic acids, polypeptides, and antibodies, and methods of using the polypeptides in various reactions for industrial or pharmaceutical applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.