Bioinformatically detectable group of novel viral regulatory genes and uses thereof
US7696342B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Aug 27, 2003 |
| Grant date | Apr 13, 2010 |
| Priority date | — |
| Expiry date | Oct 30, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/701
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a group of novel viral RNA regulatory genes, here identified as “viral genomic address messenger genes” or “VGAM genes”, and as “genomic record” or “GR” genes. VGAM genes selectively inhibit translation of known host target genes, and are believed to represent a novel pervasive viral attack mechanism. GR genes encode an operon-like cluster of VGAM genes. VGAM and viral GR genes may therefore be useful in diagnosing, preventing and treating viral disease. Several nucleic acid molecules are provided respectively encoding several VGAM genes, as are vectors and probes, both comprising the nucleic acid molecules, and methods and systems for detecting VGAM genes, and for counteracting their activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.