Method for opening tight junctions
US7696343B2 · kind B2 · utility
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14References
6Claims
0Family size
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Key dates
| Filing date | Jan 18, 2007 |
| Grant date | Apr 13, 2010 |
| Priority date | — |
| Expiry date | Jun 30, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The use of antagonists to JAM-1 Claudin-4 and occludin to open tight junctions. The antagonists include, by way of example antibodies and antibody fragments that bind to the proteins and small interfering nucleic acids that downregulate the mRNA encoding the proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.