Patent · US Active

Alternative dimerisation reagents for synthesis of iodixanol

US7696381B1 · kind B1 · utility

0Cited by

1References

3Claims

0Family size

Assignee

GE HEALTHCARE AS · NO

Inventors

Arne Berg · Sandvika, NO
Harald Dugstad · Oslo, NO
Michel Gacek · Oslo, NO
Trygve Gulbrandsen · Sandvika, NO
Per Strande · Oslo, NO

Key dates

Filing date	Sep 24, 2009
Grant date	Apr 13, 2010
Priority date	—
Expiry date	Sep 24, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C231/12
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

This invention relates generally to non-ionic X-ray contrast agents. It further relates to the synthesis of iodixanol. In particular, it relates to alternative dimerisation reagents in the conversion of 5-acetamido-N,N′-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide (“Compound A”) to iodixanol.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.