Patent · US Active

Alcohol dehydrogenases

US7700311B2 · kind B2 · utility

0Cited by

2References

20Claims

0Family size

Assignee

Degussa AG · DE

Inventors

Renate Schulze · Bensheim, DE
Patrick Lorenz · Lorsch, DE
Jürgen Eck · Bensheim, DE
Oliver May · Frankfurt, DE
Harald Groger · Hanau, DE
Harald Trauthwein · Munich, DE

Key dates

Filing date	Mar 10, 2005
Grant date	Apr 20, 2010
Priority date	—
Expiry date	Nov 14, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y101/01002
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to novel polypeptides which have the biological activity of an NAD- or NADP-dependent alcohol dehydrogenase. The invention furthermore relates to nucleic acids encoding said polypeptides, to nonhuman hosts or host cells and to reaction systems which may be used for preparing desired products. The polypeptides of the invention are preferably used in the preparation, starting from aldehydes or ketones, of primary and enantiomerically pure secondary alcohols which may serve as intermediates for medicaments. Alternatively, the polypeptides of the invention may also be employed in the reverse reaction, i.e. the oxidation of alcohols with the formation of aldehydes or ketones.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.