SMAD7 inhibitors for the treatment of CNS diseases

US7700572B2 · kind B2 · utility

Assignee

• Giuliani International Limited · IE

Inventors

• Andreas Steinbrecher · Regensburg, DE
• Gerhard Giegerich · Altötting, DE
• Ingo Kleiter · Regensburg, DE
• Markus Horn · Sinzing, DE
• Rainer Apfel · Sinzing, DE
• Roland Kreutzer · Weidenberg, DE
• Stefan Limmer · Neudrossenfeld, DE
• Hans-Peter Vornlocher · Bayreuth, DE

Key dates

• Filing date: Oct 31, 2002
• Grant date: Apr 20, 2010
• Expiry date: Jun 5, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2310/53
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to the use of a specific inhibitor of Smad7 expression or function for the preparation of a pharmaceutical composition for the prevention, amelioration or treatment of a disease of the central nervous system and/or diseases related and/or caused by said disease of the central nervous system. Furthermore, methods for preventing, ameliorating and/or treating such diseases are disclosed.