Imidazo- and triazolo-pyridine compounds and methods of use thereof
US7700593B2 · kind B2 · utility
33Cited by
7References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 5, 2007 |
| Grant date | Apr 20, 2010 |
| Priority date | — |
| Expiry date | Dec 18, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation and related conditions. The compounds have a general Formula Iwherein A, B, R1, R2, R3 and R4 are defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, uses of such compounds and compositions for treatment of P38 map kinase mediated diseases including rheumatoid arthritis, psoriasis and other inflammation disorders, as well as intermediates and processes useful for the preparation of compounds of Formula I.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.