Pseudopolymorphic forms of a HIV protease inhibitor

US7700645B2 · kind B2 · utility

Assignee

• Tibotec Pharmaceuticals Ltd. · IE

Inventors

• Hans Wim Pieter Vermeersch · Evergem, BE
• Daniel Joseph Christiaan Thone · Beerse, BE
• Luc Donne Marie-Louise Janssens · Malle, BE

Key dates

• Filing date: May 16, 2003
• Grant date: Apr 20, 2010
• Expiry date: Dec 26, 2026

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P31/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed.