Arctic β amyloid protofibril
US7700719B2 · kind B2 · utility
9Cited by
18References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 18, 2007 |
| Grant date | Apr 20, 2010 |
| Priority date | — |
| Expiry date | Apr 28, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/505
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to prevention and treatment of Alzheimer's disease (AD). More specifically, the invention relates to use of a non-wild type protofibril or compound(s) with protofibril forming activity for active immunisation in the purpose of treating or preventing AD. The invention further relates to a peptide, Aβ-Arc, with high protofibril forming activity as well as several applications thereof, such as antibodies against said peptide for passive immunisation against AD.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.