Connexin allele detection assays
US7700750B2 · kind B2 · utility
17Cited by
17References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 9, 2004 |
| Grant date | Apr 20, 2010 |
| Priority date | — |
| Expiry date | Feb 9, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods for the detection and characterization of mutations associated with non-syndromic hearing impairment. More particularly, the present invention provides compositions, methods and kits for using invasive cleavage structure assays (e.g. the INVADER assay) to screen nucleic acid samples, e.g., from patients, for the presence of any one of a collection of mutations in the Connexin 26, or gap junction beta 2, gene associated with non-syndromic hearing loss.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.