Indoline amide derivatives as EP4 receptor ligands
US7705035B2 · kind B2 · utility
7Cited by
1References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 8, 2007 |
| Grant date | Apr 27, 2010 |
| Priority date | — |
| Expiry date | Jun 8, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention is directed to indoline amide derivatives of formula Ias EP4 receptor ligands, antagonists or agonists, useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis, cancer and glaucoma. Pharmaceutical compositions and methods of use are also included.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.