Reagents for highly specific detection of peroxynitrite
US7705040B2 · kind B2 · utility
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61Claims
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Key dates
| Filing date | Oct 7, 2005 |
| Grant date | Apr 27, 2010 |
| Priority date | — |
| Expiry date | Dec 6, 2028 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/17
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention provides compositions which specifically reacts with peroxynitrite rather than other reactive oxygen species and reactive nitrogen species. This invention also provides related agents for measuring peroxynitrite. This invention also provides related methods for measuring peroxynitrite in a sample, high-throughput screening fluorescent methods for detecting peroxynitrite and high-throughput methods for screening compounds that increase or decrease the production of peroxynitrite comprising using such compositions and agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.