Patent · US Active

Antibodies directed to HER-3 and uses thereof

US7705130B2 · kind B2 · utility

40Cited by

36References

29Claims

0Family size

Assignees

U3 Pharma GmbH · DE
AMGEN INC. · US

Inventors

Mike Rothe · San Mateo, US
Martin Treder · Heidelberg, DE
Susanne Hartmann · Munich, DE
Eric Borges · Weitensfeld im Gurktal, AT
Larry Green · San Francisco, US

Key dates

Filing date	Jan 3, 2007
Grant date	Apr 27, 2010
Priority date	—
Expiry date	Aug 6, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2800/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to binding proteins that bind to HER-3 and polynucleotides encoding the same. Expression vectors and host cells comprising the same for the production of the binding protein of the invention are also provided. In addition, the invention provides compositions and methods for diagnosing and treating diseases associated with HER-3 mediated signal transduction and/or its ligand heregulin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.