Hepatitis C inhibitor peptide analogs
US7705146B2 · kind B2 · utility
4Cited by
3References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 22, 2005 |
| Grant date | Apr 27, 2010 |
| Priority date | — |
| Expiry date | Feb 19, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0827
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to compounds of formula (I) wherein R′, R2, R3, R4, R5, R6, Y, n and m are as defined herein. The compounds are useful for the treatment and prevention of hepatitis C viral infections in mammals by inhibiting HCV NS3 protease. The invention further relates to azalactone compounds of the formula (III) which can be reacted with an amide anion to produce the compounds of formula (I).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.