Portable reactor for real-time nucleic acid amplification and detection comprising a reaction chamber formed from a flexible printed circuit board
US7705339B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 25, 2007 |
| Grant date | Apr 27, 2010 |
| Priority date | — |
| Expiry date | Apr 30, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/645
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides core technologies necessary for a portable, low cost LED-based handheld fluorometer. The fluorometer is based on a heater integrated within the walls of the reaction chamber, and an orthogonal geometry LED based light source to provide optical excitation. Power is supplied through either an internal power supply, and data is collected in real-time through standard serial interfaces of personal computers, which can also be used to provide power, or personal digital assistants. Thermal regulation is automatically maintained using temperature sensor feedback control. Such a handheld system can allow applications requiring temperature sensitive photometric measurements for real time analyte detection to be performed in the field.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.