Models for vaccine assessment
US7709257B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 27, 2007 |
| Grant date | May 4, 2010 |
| Priority date | — |
| Expiry date | Jul 23, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/0337
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to methods for constructing and using in vivo and in vitro models of aspects of human immunity and, in particular, construction of a human immune system model for the testing of, for example, vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals. The present invention comprises both in vivo and in vitro models of aspects of human immunity that are useful for assessing the interaction of substances with the immune system, and thus can be used to accelerate and improve the accuracy and predictability of, for example, vaccine, drug, biologic, immunotherapy, cosmetic and chemical development. The invention is also useful for the generation of human monoclonal and polyclonal antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.