Patent · US Active

Control of function of intracellular Ca ion

US7709441B2 · kind B2 · utility

0Cited by

1References

4Claims

0Family size

Assignee

Japan Science and Technology Agency · JP

Inventors

Katsuhiko Mikoshiba · Saitama, JP
Junji Hirota · Osaka, JP
Hideaki Ando · Moriyama, JP

Key dates

Filing date	Jun 11, 2007
Grant date	May 4, 2010
Priority date	—
Expiry date	Dec 16, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K14/4702
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Analysis of substance capable of binding with inositol-1,4,5-triphosphate (IP3) receptor (IP3R), preferably with a regulation domain of IP3R; analysis of the function of IP3R; and establishing of a method of treatment or diagnosis for various malfunctions and diseases associated with IP3R. In particular, control of the activity of intracellular Ca2+ release. More specifically, a regulator for the activity of inositol-1,4,5-triphosphate (IP3) receptor (IP3R), comprised of carbonic anhydrase related protein (CARP); a control agent for intracellular calcium release, comprised of carbonic anhydrase related protein (CARP); and a method of control therewith.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.