Diarylhydantoin compounds

US7709517B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Charles L. Sawyers · New York, US
• Michael E. Jung · Los Angeles, US
• Charlie D. Chen · Los Angeles, US
• Samedy Ouk · San Diego, US
• Derek Welsbie · Rancho Santa Fe, US
• Chris Tran · New York, US
• John Wongvipat · Nanuet, US
• Dongwon Yoo · Los Angeles, US

Key dates

• Filing date: May 15, 2006
• Grant date: May 4, 2010
• Expiry date: Dec 28, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.