Compositions and methods for enhancing contrast in imaging
US7713517B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 21, 2004 |
| Grant date | May 11, 2010 |
| Priority date | — |
| Expiry date | Dec 5, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/0466
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Example compositions of liposomes with hydrophilic polymers on their surface, and containing relatively high concentrations of contrast-enhancing agents for computed tomography are provided. Example pharmaceutical compositions of such liposomes, when administered to a subject, provide for increased contrast of extended duration, as measured by computed tomography, in the bloodstream and other tissues of the subject. Also provided are example methods for making the liposomes containing high concentrations of contrast-enhancing agents, and example methods for using the compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.