Method of deprotection
US7714115B2 · kind B2 · utility
5Cited by
3References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 23, 2005 |
| Grant date | May 11, 2010 |
| Priority date | — |
| Expiry date | Oct 5, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/05
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a method for the synthesis of an 18F-labelled product comprising deprotected of a protected 18F-labelled compound using a deprotection agent comprising a weak acid and wherein neutralisation and buffering of the deprotected product are carried out by the addition of a neutralisation agent. The deprotected product is buffered in a pH range suitable for subsequent autoclaving and formulation into an injectable radiopharmaceutical.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.