Use of compounds and compositions for the treatment of amyloid diseases
US7714170B2 · kind B2 · utility
4Cited by
2References
23Claims
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Key dates
| Filing date | Dec 8, 2008 |
| Grant date | May 11, 2010 |
| Priority date | — |
| Expiry date | Dec 8, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, especially Aβ amyloidosis, such as observed in Alzheimer's disease, use in the reduction of Aβ peptide in vivo, use in modulating APP processing, and use in modulating the activity of APP secretase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.