Composition (RCUD) for protecting and/or repairing DNA from oxidative damages and a method thereof

US7718360B2 · kind B2 · utility

Assignee

• COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH · IN

Inventors

• Tapan Chakrabarti · Nagpur, IN
• Saravana Devi Sivanesan · Nagpur, IN
• Krishnamurthi Kannan · Nagpur, IN
• Dipanwita Dutta · Nagpur, IN
• Rishi Singh · Nagpur, IN
• Sunil Balkrishna Mansinghka · Jamkhed, IN
• Suresh Haribhau Dawle · Nagpur, IN

Key dates

• Filing date: Apr 2, 2003
• Grant date: May 18, 2010
• Expiry date: Apr 2, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K35/22
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A composition useful for protecting and/or repairing DNA from oxidative damages said composition comprising redistilled cow's urine distillate (RCUD) having components benzoic acid, and hexanoic acid, with ammonia content of the composition ranging between 5-15 mg/L, and optionally along with anti-oxidants; and a method of protecting and/or repairing DNA from oxidative damages using composition of claim 1, said method comprising steps of estimating the amount of folded DNA in a sample, mixing the said composition to the said DNA either before or after the exposure of the DNA to the oxidatively DNA-damaging agent, and determining percentage folded DNA in the mixture showing protection and/or repair of DNA from oxidative damages.