Immunostimulatory oligonucleotide that induces interferon alpha
US7718623B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Feb 25, 2005 |
| Grant date | May 18, 2010 |
| Priority date | — |
| Expiry date | Feb 25, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/55561
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An immunostimulatory oligonucleotide that is represented by the general formula 5′-Gm-GACGATCGTC-Gn-3′ or 5′-Gm-CACGATCGTG-Gn-3′ (in the formula, m and n are each independently an integer from 1 to 9 and m+n=10) and that comprises any of the following base sequences: GGACGATCGTCGGGGGGGGG (SEQ. ID. NO.: 1), GGGACGATCGTCGGGGGGGG (SEQ. ID. NO.: 2), GGGGACGATCGTCGGGGGGG (SEQ. ID. NO.: 3), GGGGGGGACGATCGTCGGGG (SEQ ID NO: 4), GGGGGGGGACGATCGTCGGG (SEQ. ID. NO.: 5), GGGGGGGGGACGATCGTCGG (SEQ. ID. NO.: 6), GGGGGGGGGGACGATCGTCG (SEQ. ID. NO.: 7), and GGGGGGGGGCACGATCGTGG (SEQ. ID. NO.: 8).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.