ErbB3 binding protein compositions and methods of use
US7718626B2 · kind B2 · utility
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24Claims
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Key dates
| Filing date | Feb 17, 2006 |
| Grant date | May 18, 2010 |
| Priority date | — |
| Expiry date | Mar 13, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of repressing a cell-cycle gene, which is regulated by an E2F transcription factor, in a cell, wherein the method comprises contacting the cell with a cell-cycle gene-repressing amount of ErbB3 binding protein (Ebp1); a method of inhibiting prostate cancer in a mammal, wherein the method comprises administering to the mammal a prostate cancer-inhibiting amount of Ebp1; a composition comprising an Ebp1-expressing viral vector that expresses a cell-cycle gene-repressing amount of Ebp1; and a composition comprising polymer-packaged DNA comprising and expressing a cell-cycle gene-repressing amount of Ebp1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.