Patent · US Active

Methods and pharmaceutical compositions for reliable achievement of acceptable serum testosterone levels

US7718640B2 · kind B2 · utility

37Cited by

5References

14Claims

0Family size

Assignee

Bayer Schering Pharma AG · DE

Inventors

Doris Hubler · Jena, DE
Sabine Fricke · Jena, DE
Jan-Peter Ingwersen · Berlin, DE
Wilhelm Kuhnz · Berlin, DE

Key dates

Filing date	Mar 12, 2004
Grant date	May 18, 2010
Priority date	—
Expiry date	Mar 14, 2027

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to pharmaceutical compositions, formulated for injectable administration, which comprises a testosterone ester, in particularly testosterone undecanoate, in a vehicle comprising castor oil and a co-solvent. Upon injecting the compositions according to a particular administration scheme, reliable levels of testosterone in serum in the normal physiological range is achieved for a long period. This allows for the use of the compositions in hormone replacement therapy and male contraception without concomitant monitoring of testosterone levels in serum by a physician.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.