Inclusion compounds of fumagillol derivative or its salt, and pharmaceutical compositions comprising the same
US7718695B2 · kind B2 · utility
49Cited by
9References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 25, 2007 |
| Grant date | May 18, 2010 |
| Priority date | — |
| Expiry date | Jul 25, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08L5/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to an inclusion compound of fumagillol derivative or its salt with hydroxypropyl-β-cyclodextrin or sulfobutylether-7-β-cyclodextrin, and pharmaceutical compositions comprising the same. The inclusion compound according to the present invention has superior water solubility and stability while exhibiting low toxicity, rendering it valuable as an anticancer agent or inhibitor of tumor metastasis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.